PROJECTS

On currently running projects and new project ideas

Prospective CSDH-REGISTRY

This Registry is a multicenter, prospective cohort study observing CSDH patients to assess their characteristics, treatment, and outcome. It aims to develop a predictive model for personalized treatment selection.

TORCH-trial: Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma.

A double-blind, placebo-controlled, multicenter, randomized clinical trial. It aims to evaluate the efficacy of TXA to prevent surgery for CSDH in patients diagnosed with CSDH for which a conservative treatment is selected as primary treatment strategy.

ELIMINATE-trial: Embolization of middle meningeal artery in chronic subdural hematoma.

A multicenter, randomized controlled open-label superiority trial. Aim is to evaluate whether additional embolization of the middle meningeal artery after surgery for CSDH reduces the recurrent surgery rate.

The international COllaborative Research Initiative on Chronic subdural hematoma (iCORIC) aims to reach consensus on a core outcome set, a standardized CSDH definition and data elements to be used in future CSDH studies.

The DSHR collaborates with iCORIC.

FINISHED PROJECTS

DECSA-trial: DExamethasone therapy in symptomatic patients with Chronic Subdural hematomA.

A prospective, multicenter, randomized controlled trial which aimed to evaluate the effect of initial dexamethasone therapy versus primary surgery on functional outcome and cost-effectiveness, in symptomatic patients with chronic subdural hematoma.

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